

| 카탈로그 번호 | HX073014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-AP2B1 Polyclonal Antibody (HX073014) is a rabbit polyclonal antibody detecting AP2B1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human AP2B1 (Met1-Phe266). | ||||||||
| 타겟 | Adaptor-related protein complex 2 subunit beta, ADTB2, CLAPB1, Beta-adaptin, AP105B, AP-2 complex subunit beta, Plasma membrane adaptor HA2/AP2 adaptin beta subunit, AP2B1, Adaptor protein complex AP-2 subunit beta, Clathrin assembly protein complex 2 beta large chain, Beta-2-adaptin | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P63010 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | AP-2 complex subunit beta (AP2B1) is a ~104 kDa protein. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. 1. Marcello, E. et al. (2013) The Journal of clinical investigation 123, 2523-38. PMID: 23676497 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-AP2B1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse cerebellum lysate
Lane 3: Mouse brain lysate
Lane 4: Rat cerebellum lysate


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