Anti-BMP3/Osteogenin Polyclonal Antibody (HY406014)

Name: Anti-BMP3/Osteogenin Polyclonal Antibody
Brand: abinScience
SKU: HY406014
Price: 168 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HY406014

설명

Anti-BMP3/Osteogenin Polyclonal Antibody (HY406014) is a rabbit polyclonal antibody detecting Osteogenin in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human BMP3/Osteogenin (Gln363-Arg472).

타겟

BMP-3, Bone morphogenetic protein 3A, Osteogenin, BMP-3A, Bone morphogenetic protein 3, BMP3, BMP3A

정제

Purified by antigen affinity column.

등록번호

P12645

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Bone morphogenetic protein 3 (BMP3/Osteogenin) is a ~53 kDa protein. Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentiation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.

1. Daluiski, A. et al. (2001) Nature genetics 27, 84-8. PMID: 11138004

2. Kang, Q. et al. (2004) Gene therapy 11, 1312-20. PMID: 15269709

3. Wen, J. et al. (2019) Journal of experimental & clinical cancer research : CR 38, 428. PMID: 31665064

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-BMP3/Osteogenin Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-BMP3/Osteogenin Polyclonal Antibody (HY406014)

개요

이미지

참고 문헌

데이터시트

SDS

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