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| 카탈로그 번호 | JN968014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Bordetella pertussis | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Bordetella pertussis ptxA/PTXS (Asp35-Phe269). | ||||||||
| 타겟 | Pertussis toxin subunit 1, PTX S1, Islet-activating protein S1, IAP S1, NAD-dependent ADP-ribosyltransferase, 2.4.2.-, ptxA, BP3783 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P04977 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pertussis toxin subunit 1 (ptxA/PTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-PT polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Bordetella pertussis ptxA/PTXS1 (Catalog No: JN968012)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
