Anti-Bordetella pertussis ptxA/PTXS1 Reference Antibody (SYN-005-1B7, RUO) (JN968016)

Name: Anti-Bordetella pertussis ptxA/PTXS1 Reference Antibody (SYN-005-1B7, RUO)
Brand: abinScience
SKU: JN968016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	JN968016
Description	SYN-005-1B7 (JN968016) is a research-grade recombinant antibody targeting ptxAPTXS1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Bordetella pertussis
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	ptxAPTXS1
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04977
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	hu1B7, SYN-005, SYN-005-1B7
Background	Pertussis toxin subunit 1 (ptxAPTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade SYN-005-1B7

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Datasheet

Anti-Bordetella pertussis ptxA/PTXS1 Reference Antibody (SYN-005-1B7, RUO).pdf

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Anti-Bordetella pertussis ptxA/PTXS1 Reference Antibody (SYN-005-1B7, RUO) (JN968016)

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