Anti-Human CCL2/MCP-1 Polyclonal Antibody (HY280014)

Name: Anti-Human CCL2/MCP-1 Polyclonal Antibody
Brand: abinScience
SKU: HY280014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HY280014

설명

Anti-CCL2/MCP-1 Polyclonal Antibody (HY280014) is a rabbit polyclonal antibody detecting MCP-1 in ELISA, IHC, WB. Suitable for Human, Macaca fascicularis, Macaca mulatta, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CCL2/MCP-1 (Gln24-Thr99).

타겟

HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2

정제

Purified by antigen affinity column.

등록번호

P13500

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171

2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439

3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883

4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247

5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182

6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674

7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CCL2/MCP-1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CCL2/MCP-1 Polyclonal Antibody (HY280014)

개요

이미지

참고 문헌

데이터시트

SDS