

| 카탈로그 번호 | HC579014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CD213a2/IL13RA2 Polyclonal Antibody (HC579014) is a rabbit polyclonal antibody detecting CD213a2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CD213a2/IL13RA2 (Pro238-Glu334). | ||||||||
| 타겟 | IL13R, IL-13RA2, IL-13 receptor subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL-13R subunit alpha-2, IL13RA2, Interleukin-13 receptor subunit alpha-2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q14627 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interleukin-13 receptor subunit alpha-2 (CD213a2/IL13RA2) is a ~44 kDa protein. Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. 1. Rahaman, SO. et al. (2002) Cancer research 62, 1103-9. PMID: 11861389 2. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 3. Fichtner-Feigl, S. et al. (2006) Nature medicine 12, 99-106. PMID: 16327802 | ||||||||
| 참고사항 | For research use only. |
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