Anti-Human CD91/LRP1 Polyclonal Antibody (HC475014)

Name: Anti-Human CD91/LRP1 Polyclonal Antibody
Brand: abinScience
SKU: HC475014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC475014

설명

Anti-CD91/LRP1 Polyclonal Antibody (HC475014) is a rabbit polyclonal antibody detecting LRP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CD91/LRP1 (Ala20-His280).

타겟

APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q07954

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor.

1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044

2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657

3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392

4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438

5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178

6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553

7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CD91/LRP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CD91/LRP1 Polyclonal Antibody (HC475014)

개요

이미지

참고 문헌

데이터시트

SDS