

| 카탈로그 번호 | HT160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CPLX1 Polyclonal Antibody (HT160014) is a rabbit polyclonal antibody detecting CPLX1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CPLX1 (Met1-Lys134). | ||||||||
| 타겟 | Complexin-1, CPLX1, CPX I, Synaphin-2, Complexin I | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O14810 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Complexin-1 (CPLX1) is a ~15 kDa protein. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. 1. Kümmel, D. et al. (2011) Nature structural & molecular biology 18, 927-33. PMID: 21785414 | ||||||||
| 참고사항 | For research use only. |
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