Anti-Human DGKZ Polyclonal Antibody (HC693014)

Name: Anti-Human DGKZ Polyclonal Antibody
Brand: abinScience
SKU: HC693014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC693014

설명

Anti-DGKZ Polyclonal Antibody (HC693014) is a rabbit polyclonal antibody detecting DGKZ in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DGKZ (Gly411-Lys624).

타겟

DAGK6, DAG kinase zeta, Diglyceride kinase zeta, DGK-zeta, Diacylglycerol kinase zeta, DGKZ

정제

Purified by antigen affinity column.

등록번호

Q13574

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Diacylglycerol kinase zeta (DGKZ) is a ~103 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Does not exhibit an acyl chain-dependent substrate specificity among diacylglycerol species. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro but less efficiently and with a preference for alkylacylglycerols containing an arachidonoyl group.

1. Epand, RM. et al. (2004) Biochemistry 43, 14778-83. PMID: 15544348

2. Epand, RM. et al. (2007) Biochemistry 46, 14225-31. PMID: 18004883

3. Lung, M. et al. (2009) The Journal of biological chemistry 284, 31062-73. PMID: 19744926

4. Shulga, YV. et al. (2011) FEBS letters 585, 4025-8. PMID: 22108654

5. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129

6. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095

7. Ding, L. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5519-24. PMID: 9159104

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human DGKZ Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human DGKZ Polyclonal Antibody (HC693014)

개요

이미지

참고 문헌

데이터시트

SDS