Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody (VK536014)

Name: Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody
Brand: abinScience
SKU: VK536014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

VK536014

설명

Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody (VK536014) is a rabbit polyclonal antibody detecting BZLF1 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Epstein-Barr virus (HHV-4) (Human herpesvirus 4)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant EBV/HHV-4 BZLF1 (Leu175-Phe245).

타겟

Lytic switch protein BZLF1, EB1, Protein Z, Trans-activator protein BZLF1, Zta, bZIP transcription factor ZEBRA, BZLF1

정제

Purified by antigen affinity column.

등록번호

P03206

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Lytic switch protein BZLF1 is a ~26 kDa protein. Transcription factor that acts as a molecular switch to induce the transition from the latent to the lytic or productive phase of the virus cycle (Probable). Mediates the switch from the latent to the lytic cycle of infection in cells containing a highly methylated viral genome. Probably binds to silenced chromatin and recruits host chromatin-remodeling enzymes. Regulates this switch by binding to 2 types of ZEBRA response elements (ZREs): the CpG-free AP-1 like elements (latency) and the methylated CpG-containing elements (lytic replication) (Probable). Activates preferentially the methylated forms of the viral lytic R (BRLF1) and Na (BRRF1) gene promoters, the latters being the first genes activated during Z-mediated reactivation in latently infected cells.

1. Schepers, A. et al. (1993) The EMBO journal 12, 3921-9. PMID: 8404860

2. Bhende, PM. et al. (2004) Nature genetics 36, 1099-104. PMID: 15361873

3. Bernaudat, F. et al. (2022) Nucleic acids research 50, 490-511. PMID: 34893887

4. Schaeffner, M. et al. (2019) Life science alliance 2. PMID: 30926617

5. Flower, K. et al. (2011) PloS one 6, e25922. PMID: 22022468

6. Dickerson, SJ. et al. (2009) PLoS pathogens 5, e1000356. PMID: 19325883

7. Feederle, R. et al. (2000) The EMBO journal 19, 3080-9. PMID: 10856251

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-BLZF1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant EBV/HHV-4 BZLF1 (Catalog No: VK536012)

참고 문헌

데이터시트

Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-EBV/HHV-4 BZLF1 Polyclonal Antibody (VK536014)

개요

이미지

참고 문헌

데이터시트

SDS

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