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Anti-Eculizumab ELISA Kit (AF687018)

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개요
카탈로그 번호AF687018
설명
Anti-Eculizumab ELISA Kit (AF687018) — Quantitative sandwich ELISA for Anti-Eculizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL.
Highlights
  • ●Sandwich Format — High specificity, reliable quantification.
  • ●Ready-to-Use — Complete kit with pre-coated plates included.
샘플 유형Plasma, Serum
범위156.25 - 10, 000 ng/mL
등록번호 P01031
응용 분야 ELISA
검출 방법 Colorimetric
분석 유형 Quantitative
회수율 80-120%
배송 2-8 ℃
안정성 및 저장 The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
사양

Eculizumab

대체 이름5G1.1, h5G1.1HuG2/G4, 219685-50-4
배경

Complement C5 (Eculizumab) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586
2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047
3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019
4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279
5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456
6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882
참고사항 For Research Use Only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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