

| 카탈로그 번호 | AF687028 |
|---|---|
| 설명 |
Anti-Eculizumab Neutralizing Antibody ELISA kit (AF687028) — Quantitative sandwich ELISA for Anti-Eculizumab Neutralizing Antibody. Sample: Plasma, Serum. Range: 15.625-1, 000 ng/ml.
Highlights
|
| 샘플 유형 | Plasma, Serum |
| 범위 | 15.625-1, 000 ng/ml |
| 등록번호 | P01031 |
| 응용 분야 | ELISA |
| 검출 방법 | Colorimetric |
| 분석 유형 | Quantitative |
| 회수율 | 80-120% |
| 배송 | 2-8 ℃ |
| 안정성 및 저장 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 사양 | Eculizumab |
| 대체 이름 | 5G1.1, h5G1.1HuG2/G4, 219685-50-4 |
| 배경 | Complement C5 (Eculizumab) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019 4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 |
| 참고사항 | For Research Use Only. |
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