

| 카탈로그 번호 | HB800014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-EGR1 Polyclonal Antibody (HB800014) is a rabbit polyclonal antibody detecting EGR1 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Cerdocyon thous, Coturnix japonica, and Danio rerio.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human EGR1 (Gln282-Ser433). | ||||||||
| 타겟 | Zinc finger protein Krox-24, EGR-1, Nerve growth factor-induced protein A, Early growth response protein 1, NGFI-A, KROX24, Transcription factor ETR103, ZNF225, Transcription factor Zif268, Zinc finger protein 225, EGR1, AT225 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P18146 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Early growth response protein 1 (EGR1) is a ~57 kDa protein. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. 1. Hu, CT. et al. (2010) The FEBS journal 277, 1202-18. PMID: 20121949 2. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363 3. Zandarashvili, L. et al. (2015) FEBS letters 589, 1748-53. PMID: 25999311 | ||||||||
| 참고사항 | For research use only. |
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