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| 카탈로그 번호 | JN084014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Escherichia coli | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Escherichia coli eae/Intimin (Lys450-Gln655). | ||||||||
| 타겟 | Intimin, Attaching and effacing protein, Eae protein, eae, eaeA, E2348C_3939 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P19809 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Intimin (eae) is a ~102 kDa protein. An inverse autotransporter. Adhesin, which mediates attachment to the human intestine epithelial cells. Necessary for the production of attaching and effacing lesions on infected human tissue culture cells. Anchored to the outer membrane by binding to peptidoglycan (PGN) via its periplasmic domain, thus helping in receptor interactions during host invasion (Probable). PGN-binding may also aid in resisting mechanical and chemical stress during transit of the bacterium through the gastrointestinal tract of the host (Probable). 1. Leo, JC. et al. (2015) Molecular microbiology 95, 80-100. PMID: 25353290 2. Weikum, J. et al. (2020) Scientific reports 10, 21249. PMID: 33277518 3. Jerse, AE. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 7839-43. PMID: 2172966 4. Batchelor, M. et al. (2000) The EMBO journal 19, 2452-64. PMID: 10835344 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-EAE polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Escherichia coli eae/Intimin (Catalog No: JN084012)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
