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Anti-FSCN1 Polyclonal Antibody (HS760014)

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개요
카탈로그 번호HS760014
설명
Anti-FSCN1 Polyclonal Antibody (HS760014) is a rabbit polyclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human FSCN1 (Gln277-Gly396).
타겟 SNL, FAN1, Fascin, 55 kDa actin-bundling protein, p55, Singed-like protein, FSCN1, HSN
정제 Purified by antigen affinity column.
등록번호 Q16658
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.

1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497
2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945
3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565
4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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