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| 카탈로그 번호 | HX950014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-GP2 Polyclonal Antibody (HX950014) is a rabbit polyclonal antibody detecting GP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GP2 (Phe307-Asn512). | ||||||||
| 타겟 | Pancreatic zymogen granule membrane protein GP-2, GP2, ZAP75, Pancreatic secretory granule membrane major glycoprotein GP2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P55259 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pancreatic secretory granule membrane major glycoprotein GP2 is a ~59 kDa protein. Functions as an intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response. | ||||||||
| 참고사항 | For research use only. |
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