Anti-GRIK2 Polyclonal Antibody (HC267014)

Name: Anti-GRIK2 Polyclonal Antibody
Brand: abinScience
SKU: HC267014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HC267014

설명

Anti-GRIK2 Polyclonal Antibody (HC267014) is a rabbit polyclonal antibody detecting GRIK2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human GRIK2 (Asn286-Pro561).

타겟

EAA4, GluR6, Glutamate receptor 6, Excitatory amino acid receptor 4, Glutamate receptor ionotropic, kainate 2, GluK2, GLUR6, GRIK2, GluR-6

정제

Purified by antigen affinity column.

등록번호

Q13002

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Glutamate receptor ionotropic, kainate 2 (GRIK2) is a ~102 kDa protein. Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformational change leading to the opening of the cation channel, converting the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Modulates cell surface expression of NETO2.

1. Hoo, KH. et al. (1994) Receptors & channels 2, 327-37. PMID: 7536611

2. Swanson, GT. et al. (1996) The Journal of physiology 492 ( Pt 1), 129-42. PMID: 8730589

3. Hayes, DM. et al. (2003) Biochemical and biophysical research communications 310, 8-13. PMID: 14511640

4. Guzmán, YF. et al. (2017) Neurology. Genetics 3, e129. PMID: 28180184

5. Stolz, JR. et al. (2021) American journal of human genetics 108, 1692-1709. PMID: 34375587

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-GRIK2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-GRIK2 Polyclonal Antibody (HC267014)

개요

이미지

참고 문헌

데이터시트

SDS