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| 카탈로그 번호 | VK646043 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV) | ||||
| 응용 분야 | ELISA, Neutralization | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, lambda | ||||
| 클론 ID | SAA2516 | ||||
| 타겟 | Envelopment polyprotein, Glycoprotein G1, Glycoprotein N | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P08668 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Envelopment polyprotein (Glycoprotein N/Gn) is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. 1. Raymond, T. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 1163-8. PMID: 15657120 2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165 3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291 4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265 5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607 6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447 | ||||
| 참고사항 | For research use only |
SDS-PAGE for Anti-Hantaan virus/HTNV Glycoprotein N/Gn Antibody (SAA2516)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
