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| 카탈로그 번호 | ZA222014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Honeybee Api m 11/MRJP1 Polyclonal Antibody (ZA222014) is a rabbit polyclonal antibody detecting MRJP1 in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Apis mellifera (Honeybee) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Honeybee Api m 11/MRJP1 (Asn20-Leu432). | ||||||||
| 타겟 | Major royal jelly protein 1, MRJP-1, MRJP1, 56-kDa protein 4, p56kP-4, Apalbumin 1, Apisin subunit MRJP1, Bee-milk protein, Royalactin, Jellein-1, Jelleine-I, Jellein-2, Jelleine-II, Jellein-4, Jelleine-IV, MRJP1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O18330 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Major royal jelly protein 1 (Api m 11/MRJP1) is a ~48 kDa protein. Most abundant protein component of royal jelly, a substance produced in the hypopharyngeal gland containing proteins, free amino acids, fatty acids, sugars and other nutrients, which is fed to developing larvae by worker nurse bees. Major royal jelly proteins (Mrjps) are high in essential amino acids and probably have a nutritional function in larval food. All larvae are fed some royal jelly (also known as worker jelly) early in their development but it forms the principal source of nutrition for larvae destined to become queen bees (Probable). Induces the differentiation of honey bee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing 20-hydroxyecdysone (ecdysterone, 20E) production. 1. Santos, KS. et al. (2005) Insect biochemistry and molecular biology 35, 85-91. PMID: 15607658 2. Tamura, S. et al. (2009) Proteomics 9, 5534-43. PMID: 20017154 3. Kamakura, M. (2011) Nature 473, 478-83. PMID: 21516106 4. Dobritzsch, D. et al. (2019) Ecology and evolution 9, 8771-8782. PMID: 31410279 5. Schmitzová, J. et al. (1998) Cellular and molecular life sciences : CMLS 54, 1020-30. PMID: 9791542 6. Buttstedt, A. et al. (2018) Current biology : CB 28, 1095-1100.e3. PMID: 29551410 | ||||||||
| 참고사항 | For research use only. |
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