Anti-HPV16 L2 Polyclonal Antibody (VK658014)

Name: Anti-HPV16 L2 Polyclonal Antibody
Brand: abinScience
SKU: VK658014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

VK658014

설명

Anti-HPV16 L2 Polyclonal Antibody (VK658014) is a rabbit polyclonal antibody detecting HPV16 L2 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human papillomavirus 16 (HPV16)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant HPV16 L2 (Arg2-Ala473(Glu43Asp)).

타겟

Minor capsid protein L2, L2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P03107

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Minor capsid protein L2 is a ~50 kDa protein. Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.

참고사항

For research use only

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