Anti-Human beta-1 Adrenergic R/ADRB1 Polyclonal Antibody (HY486014)

Name: Anti-Human beta-1 Adrenergic R/ADRB1 Polyclonal Antibody
Brand: abinScience
SKU: HY486014
Price: 168 USD
Availability: InStock

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사양:

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100ug

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY486014

설명

Anti-Human ADRB1 Polyclonal Antibody (HY486014) is a rabbit polyclonal antibody detecting ADRB1. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ADRB1 (Gly2-Gln55&His197-Arg222).

타겟

ADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

P08588

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes.

1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248

2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161

3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775

4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660

5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857

6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867

7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human beta-1 Adrenergic R/ADRB1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human beta-1 Adrenergic R/ADRB1 Polyclonal Antibody (HY486014)

개요

이미지

참고 문헌

데이터시트

SDS