Anti-Human ARFIP2 Polyclonal Antibody (HD593014)

Name: Anti-Human ARFIP2 Polyclonal Antibody
Brand: abinScience
SKU: HD593014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD593014

설명

Anti-Human ARFIP2 Polyclonal Antibody (HD593014) is a rabbit polyclonal antibody detecting ARFIP2. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ARFIP2 (Gly81-Gln341).

타겟

ADP-ribosylation factor-interacting protein 2, ARFIP2, Arfaptin-2, POR1, Partner of RAC1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P53365

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Arfaptin-2 (ARFIP2) is a ~37 kDa protein. Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.

1. Eiseler, T. et al. (2016) The Journal of biological chemistry 291, 462-77. PMID: 26507660

2. Judith, D. et al. (2019) The Journal of cell biology 218, 1634-1652. PMID: 30917996

3. Judith, D. et al. (2019) Autophagy 15, 1660-1661. PMID: 31204568

4. Nguyen, TN. et al. (2021) Molecular cell 81, 2013-2030.e9. PMID: 33773106

5. You, DJ. et al. (2015) Cellular signalling 27, 2173-81. PMID: 26296658

참고사항

For research use only

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참고 문헌

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Anti-Human ARFIP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ARFIP2 Polyclonal Antibody (HD593014)

개요

이미지

참고 문헌

데이터시트

SDS