Anti-Human ARL3 Polyclonal Antibody (HW758014)

Name: Anti-Human ARL3 Polyclonal Antibody
Brand: abinScience
SKU: HW758014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HW758014

설명

Anti-Human ARL3 Polyclonal Antibody (HW758014) is a rabbit polyclonal antibody detecting ARL3 in ELISA, IHC, WB. Suitable for Bovine, Danio rerio, Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ARL3 (Met1-Lys182).

타겟

ARFL3, ADP-ribosylation factor-like protein 3, ARL3

정제

Purified by antigen affinity column.

등록번호

P36405

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

ADP-ribosylation factor-like protein 3 (ARL3) is a ~20 kDa protein. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E. Targets NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium.

1. Zhou, C. et al. (2006) Molecular biology of the cell 17, 2476-87. PMID: 16525022

2. Veltel, S. et al. (2008) FEBS letters 582, 2501-7. PMID: 18588884

3. Wright, KJ. et al. (2011) Genes & development 25, 2347-60. PMID: 22085962

4. Alkanderi, S. et al. (2018) American journal of human genetics 103, 612-620. PMID: 30269812

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-ARL3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate

참고 문헌

데이터시트

Anti-Human ARL3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ARL3 Polyclonal Antibody (HW758014)

개요

이미지

참고 문헌

데이터시트

SDS

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