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| 카탈로그 번호 | HX250065 |
|---|---|
| 설명 |
Anti-Human B2M Monoclonal Antibody (1A063) [1A063] (HX250065) is a mouse monoclonal antibody detecting B2M in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, IHC, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG1 |
| 클론 ID | 1A063 |
| 면역원 | Mammalian cells - derived recombinant Human B2M (Met1-Met119). |
| 타겟 | Beta-2-microglobulin, B2M, |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P61769 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. 1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human B2M Monoclonal Antibody (1A063)
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