Anti-Human B4GALNT2 Polyclonal Antibody (HP667014)

Name: Anti-Human B4GALNT2 Polyclonal Antibody
Brand: abinScience
SKU: HP667014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HP667014

설명

Anti-Human B4GALNT2 Polyclonal Antibody (HP667014) is a rabbit polyclonal antibody detecting B4GALNT2. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human B4GALNT2 (Thr324-Ala566).

타겟

B4GALNT2, Beta-1,4 N-acetylgalactosaminyltransferase 2, EC:2.4.1.-, GALGT2, Sd(a) beta-1,4-GalNAc transferase, UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q8NHY0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Beta-1,4 N-acetylgalactosaminyltransferase 2 (B4GALNT2) is a ~63 kDa protein. Beta-1,4 N-acetylgalactosaminyltransferase involved in the biosynthesis of Sd(a) histo-blood group antigen. Catalyzes the transfer of N-acetylgalactosamine (GalNAc) group in a beta-1,4-linkage from UDP-GalNAc to the galactose residue of NeuAcalpha2->3Gal-R to form Sd(a) glycan epitope GalNAcbeta1->4(NeuAcalpha2->3)Gal-R. The Sd(a) epitope is carried in O- and N-linked glycoproteins and glycolipids, including O-linked core 1 structures on GYPA/glycophorin, SLC4A1 and SLC29A1 in erythrocytes, N-linked glycans attached to the Tamm-Horsfall glycoprotein UMOD/uromodulin in renal fluids, O-linked core 3 glycans on mucins in colon and neolactosides in gastric mucosa. Confers protection against influenza A virus strains that attach to NeuAcalpha2->3-carrying host receptors. Modifies N-glycan chains on host receptors and prevents virus entry into cells.

1. Montiel, MD. et al. (2003) The Biochemical journal 373, 369-79. PMID: 12678917

2. Lo Presti, L. et al. (2003) Journal of biochemistry 134, 675-82. PMID: 14688233

3. Kawamura, YI. et al. (2005) Cancer research 65, 6220-7. PMID: 16024623

4. Stenfelt, L. et al. (2022) International journal of molecular sciences 23. PMID: 35409292

5. Heaton, BE. et al. (2017) Cell reports 20, 1503-1512. PMID: 28813663

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human B4GALNT2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human B4GALNT2 Polyclonal Antibody (HP667014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기