Anti-Human C3aR Polyclonal Antibody (HS803014)

Name: Anti-Human C3aR Polyclonal Antibody
Brand: abinScience
SKU: HS803014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HS803014

설명

Anti-Human C3AR1 Polyclonal Antibody (HS803014) is a rabbit polyclonal antibody detecting C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R; C3AR1; AZ3B; C3R1; HNFAG09 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human C3AR1 (Arg161-Arg340).

타겟

C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R; C3AR1; AZ3B; C3R1; HNFAG09

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q16581

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase.

1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936

2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260

3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human C3aR Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human C3aR Polyclonal Antibody (HS803014)

개요

이미지

참고 문헌

데이터시트

SDS