Anti-Human CBX5 Polyclonal Antibody (HW777024)

Name: Anti-Human CBX5 Polyclonal Antibody
Brand: abinScience
SKU: HW777024
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW777024

설명

Anti-Human CBX5 Polyclonal Antibody (HW777024) is a rabbit polyclonal antibody detecting CBX5. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CBX5 (Tyr20-Ser191).

타겟

Antigen p25, CBX5, Chromobox protein homolog 5, HP1 alpha, HP1A, Heterochromatin protein 1 homolog alpha

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P45973

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Chromobox protein homolog 5 (CBX5) is a ~22 kDa protein. Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Also recognizes and binds histone H1.4 methylated at 'Lys-26' (H1.4K26me). Excluded from chromatin when histone H1.4 is Simultaneously methylated at Lys-26 (H1.4K26me) and phosphorylated at Ser-27 (H1.4S27Ph). May contribute to the association of heterochromatin with the inner nuclear membrane by interactions with the lamin-B receptor (LBR).

1. Zhou, L. et al. (2025) Science (New York, N.Y.) 389, 309-316. PMID: 40440427

2. Dawson, MA. et al. (2009) Nature 461, 819-22. PMID: 19783980

3. Daujat, S. et al. (2005) The Journal of biological chemistry 280, 38090-5. PMID: 16127177

4. Kiyomitsu, T. et al. (2010) The Journal of cell biology 188, 791-807. PMID: 20231385

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CBX5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CBX5 Polyclonal Antibody (HW777024)

개요

이미지

참고 문헌

데이터시트

SDS