

| 카탈로그 번호 | HY346137 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a |
| 클론 ID | SAA0456 |
| 접합 | APC |
| 타겟 | TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC |
| 등록번호 | P13501 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). 1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064 2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218 3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620 4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373 5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414 6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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