Anti-Human CD151 Recombinant Antibody (TS151), APC (HW567137)

Name: Anti-Human CD151 Recombinant Antibody (TS151), APC
Brand: abinScience
SKU: HW567137
Price: 290 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50T
100T

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HW567137
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	TS151
접합	APC
타겟	CD151, PETA-3, Membrane glycoprotein SFA-1, GP27, Tspan-24, Platelet-endothelial tetraspan antigen 3, CD151 antigen, Tetraspanin-24, TSPAN24
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
등록번호	P48509
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	CD151 antigen is a ~28 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays a role in various cellular and molecular mechanism through its association with both integrin and non-integrin proteins. These interactions facilitate critical cellular functions, including cell-to-cell communication, wound healing, platelet aggregation, trafficking, cell motility, and angiogenesis. Via interaction with JAM-A/F11R and integrin ITGA3:ITGB1, promotes the recruitment of signaling molecules such as RAC1, CDC42 and RhoGTPases to facilitate the polarization of epithelial cells and the reorganization of the actin cytoskeleton, which are critical steps in cell migration process. Regulates the glycosylation pattern of ITGA3:ITGB1 thereby modulating its activity. 1. Zheng, ZZ. et al. (2007) The international journal of biochemistry & cell biology 39, 340-8. PMID: 17045834 2. Rocha-Perugini, V. et al. (2014) European journal of immunology 44, 1967-75. PMID: 24723389 3. Te Molder, L. et al. (2019) Journal of cell science 132. PMID: 31488507 4. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693 5. Thölmann, S. et al. (2022) Cellular and molecular life sciences : CMLS 79, 88. PMID: 35067832 6. Baldwin, G. et al. (2008) The Journal of biological chemistry 283, 35445-54. PMID: 18852263 7. Karamatic Crew, V. et al. (2004) Blood 104, 2217-23. PMID: 15265795
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

Flow CytoMetry

Flow-cytometry using APC anti-human CD151 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD151 monoclonal antibody (Catalog: HW567137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

참고 문헌

데이터시트