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| 카탈로그 번호 | HV416035 |
|---|---|
| 설명 |
Anti-Human CD2AP Monoclonal Antibody (1A676) [1A676] (HV416035) is a mouse monoclonal antibody detecting CD2AP in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, IHC, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | 1A676 |
| 면역원 | E. coli - derived recombinant human CD2AP (Val2-Lys58). |
| 타겟 | CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q9Y5K6 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | CD2-associated protein (CD2AP) is a ~71 kDa protein. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. 1. Kirsch, KH. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 6211-6. PMID: 10339567 2. Monzo, P. et al. (2005) Molecular biology of the cell 16, 2891-902. PMID: 15800069 3. Elbediwy, A. et al. (2012) The Journal of cell biology 198, 677-93. PMID: 22891260 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CD2AP Monoclonal Antibody (1A676)
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