Anti-Human Fc gamma RIIB/CD32b Recombinant Antibody (SAA0547) (HB103107)

Name: Anti-Human Fc gamma RIIB/CD32b Recombinant Antibody (SAA0547)
Brand: abinScience
SKU: HB103107
Price: 196 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HB103107
종 반응성	Human
응용 분야	ELISA, FCM, IHC, WB
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	SAA0547
테스트된 응용 분야	FCM
타겟	IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, RHD97901
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P31994
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis.
참고사항	For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Human CD32b/FCGR2B Antibody (SAA0547)
Bioactivity

SEC-HPLC detection for Anti-Human CD32b/FCGR2B Antibody (ABS0184).
Flow Cytometry

Flow-cytometry using anti-human CD32b antibody.CD32b Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD32b antibody monoclonal antibody (Catalog # HB103107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.