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| 카탈로그 번호 | HV277107 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | 2.59# |
| 타겟 | TIM, Kidney injury molecule 1, T-cell immunoglobulin mucin receptor 1, KIM1, KIM-1, TIM1, TIMD1, HAVCR1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell membrane protein 1, CD365, Hepatitis A virus cellular receptor 1, HAVcr-1, TIMD-1, TIM-1 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q96D42 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Hepatitis A virus cellular receptor 1 (CD365/KIM-1) is a ~39 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. 1. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780 2. Ichimura, T. et al. (2008) The Journal of clinical investigation 118, 1657-68. PMID: 18414680 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#)
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