Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Recombinant Antibody (2.59#), FITC (HV277117)

Name: Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Recombinant Antibody (2.59#), FITC
Brand: abinScience
SKU: HV277117
Price: 223 USD
Availability: InStock

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Overview

Catalog No.	HV277117
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	2.59#
Conjugation	FITC
Clonality	Monoclonal
Target	TIM, Kidney injury molecule 1, T-cell immunoglobulin mucin receptor 1, KIM1, KIM-1, TIM1, TIMD1, HAVCR1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell membrane protein 1, CD365, Hepatitis A virus cellular receptor 1, HAVcr-1, TIMD-1, TIM-1
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
Accession	Q96D42
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Hepatitis A virus cellular receptor 1 (CD365/KIM-1) is a ~39 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. 1. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780 2. Ichimura, T. et al. (2008) The Journal of clinical investigation 118, 1657-68. PMID: 18414680
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Recombinant Antibody (2.59#), FITC.pdf

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Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Recombinant Antibody (2.59#), FITC (HV277117)

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