Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#) (HV277107)

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Catalog No.	HV277107
Description	Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#) [2.59#] (HV277107) is a mouse monoclonal antibody detecting HAVCR1 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	2.59#
Clonality	Monoclonal
Target	TIM, Kidney injury molecule 1, T-cell immunoglobulin mucin receptor 1, KIM1, KIM-1, TIM1, TIMD1, HAVCR1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell membrane protein 1, CD365, Hepatitis A virus cellular receptor 1, HAVcr-1, TIMD-1, TIM-1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96D42
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Hepatitis A virus cellular receptor 1 (CD365/KIM-1) is a ~39 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. 1. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780 2. Ichimura, T. et al. (2008) The Journal of clinical investigation 118, 1657-68. PMID: 18414680
Note	For research use only.

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SDS-PAGE for Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#)

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Datasheet

Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#).pdf

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Anti-Human CD365/KIM-1/TIM-1/HAVCR1 Antibody (2.59#) (HV277107)

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