Anti-Human CDT1 Polyclonal Antibody (HD509014)

Name: Anti-Human CDT1 Polyclonal Antibody
Brand: abinScience
SKU: HD509014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HD509014

설명

Anti-Human CDT1 Polyclonal Antibody (HD509014) is a rabbit polyclonal antibody detecting CDT1. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CDT1 (Thr112-Ser386).

타겟

CDT1, DNA replication factor Cdt1, DUP, Double parked homolog

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9H211

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

DNA replication factor Cdt1 is a ~60 kDa protein. Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene.

1. Wohlschlegel, JA. et al. (2000) Science (New York, N.Y.) 290, 2309-12. PMID: 11125146

2. Sugimoto, N. et al. (2004) The Journal of biological chemistry 279, 19691-7. PMID: 14993212

3. Miotto, B. et al. (2011) Molecular cell 44, 62-71. PMID: 21856198

4. Varma, D. et al. (2012) Nature cell biology 14, 593-603. PMID: 22581055

5. Franz, A. et al. (2016) Nature communications 7, 10612. PMID: 26842564

6. Cook, JG. et al. (2004) The Journal of biological chemistry 279, 9625-33. PMID: 14672932

참고사항

For research use only

이미지

Western blot

Lane 1: HCT116 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: K562 cell lysate
Lane 4: MCF-7 cell lysate
Lane 5: Hela cell lysate

참고 문헌

데이터시트

Anti-Human CDT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CDT1 Polyclonal Antibody (HD509014)

개요

이미지

참고 문헌

데이터시트

SDS