Human CDT1 Recombinant Protein (N-His) (HD509012)

Name: Human CDT1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD509012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD509012
Description	Recombinant Human CDT1 Protein, N-His (HD509012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9H211
Protein length	Thr112-Ser386
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CDT1, DNA replication factor Cdt1, DUP, Double parked homolog
Background	DNA replication factor Cdt1 is a ~60 kDa protein. Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene. 1. Wohlschlegel, JA. et al. (2000) Science (New York, N.Y.) 290, 2309-12. PMID: 11125146 2. Sugimoto, N. et al. (2004) The Journal of biological chemistry 279, 19691-7. PMID: 14993212 3. Miotto, B. et al. (2011) Molecular cell 44, 62-71. PMID: 21856198 4. Varma, D. et al. (2012) Nature cell biology 14, 593-603. PMID: 22581055 5. Franz, A. et al. (2016) Nature communications 7, 10612. PMID: 26842564 6. Cook, JG. et al. (2004) The Journal of biological chemistry 279, 9625-33. PMID: 14672932
Note	For research use only

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Datasheet

Human CDT1 Recombinant Protein (N-His).pdf

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Human CDT1 Recombinant Protein (N-His) (HD509012)

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