Anti-Human CEP290 Polyclonal Antibody (HT321014)

Name: Anti-Human CEP290 Polyclonal Antibody
Brand: abinScience
SKU: HT321014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT321014

설명

Anti-Human CEP290 Polyclonal Antibody (HT321014) is a rabbit polyclonal antibody detecting CEP290 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CEP290 (Thr1289-Arg1416).

타겟

Nephrocystin-6, KIAA0373, CEP290, Bardet-Biedl syndrome 14 protein, Tumor antigen se2-2, BBS14, NPHP6, Centrosomal protein of 290 kDa, Cancer/testis antigen 87, Cep290, CT87

정제

Purified by antigen affinity column.

등록번호

O15078

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Centrosomal protein of 290 kDa (CEP290) is a ~290 kDa protein. Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.

1. Tsang, WY. et al. (2008) Developmental cell 15, 187-97. PMID: 18694559

2. Kobayashi, T. et al. (2014) The Journal of cell biology 204, 215-29. PMID: 24421332

3. Frank, V. et al. (2008) Human mutation 29, 45-52. PMID: 17705300

4. Barbelanne, M. et al. (2015) Human molecular genetics 24, 2185-200. PMID: 25552655

5. Sayer, JA. et al. (2006) Nature genetics 38, 674-81. PMID: 16682973

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CEP290 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CEP290 Polyclonal Antibody (HT321014)

개요

이미지

참고 문헌

데이터시트

SDS