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| 카탈로그 번호 | HD664014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human CEP63 Polyclonal Antibody (HD664014) is a rabbit polyclonal antibody detecting CEP63. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CEP63 (Met1-Ile309). | ||||||||
| 타겟 | CEP63, Centrosomal protein of 63 kDa, Cep63 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q96MT8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Centrosomal protein of 63 kDa (CEP63) is a ~81 kDa protein. Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. 1. Löffler, H. et al. (2011) Cancer research 71, 2129-39. PMID: 21406398 2. Sir, JH. et al. (2011) Nature genetics 43, 1147-53. PMID: 21983783 3. Kodani, A. et al. (2015) eLife 4. PMID: 26297806 4. Kodani, A. et al. (2022) EMBO reports 23, e52211. PMID: 35793002 5. Ling, H. et al. (2022) Oncogene 41, 4433-4445. PMID: 35989368 | ||||||||
| 참고사항 | For research use only |
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