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| 카탈로그 번호 | HF508013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, IF, IP | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a | ||||
| 클론 ID | SAA0198 | ||||
| 타겟 | WD repeat-containing protein 39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WDR39, CIA1, CIAO1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O76071 | ||||
| RRID | Anti-Human CIAO1 IP Antibody (SAA0198) (abinScience Cat# HF508013, RRID:AB_3729732) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a ~37 kDa protein. Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. 1. Srinivasan, V. et al. (2007) Structure (London, England : 1993) 15, 1246-57. PMID: 17937914 2. Stehling, O. et al. (2013) Cell metabolism 18, 187-98. PMID: 23891004 3. Maio, N. et al. (2024) The Journal of clinical investigation 134. PMID: 38950322 4. Johnstone, RW. et al. (1998) The Journal of biological chemistry 273, 10880-7. PMID: 9556563 5. Ito, S. et al. (2010) Molecular cell 39, 632-40. PMID: 20797633 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CIAO1 IP Antibody (SAA0198)
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