Anti-Human CX3CL1/Fractalkine Polyclonal Antibody (HX143014)

Name: Anti-Human CX3CL1/Fractalkine Polyclonal Antibody
Brand: abinScience
SKU: HX143014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX143014

설명

Anti-Human CX3CL1/Fractalkine Polyclonal Antibody (HX143014) is a rabbit polyclonal antibody detecting Fractalkine in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CX3CL1/Fractalkine (Asp90-Gln245).

타겟

Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Processed fractalkine, CX3CL1, FKN, NTT, SCYD1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

P78423

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Fractalkine (CX3CL1) is a ~42 kDa protein. Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230

2. Xue, X. et al. (2011) PLoS pathogens 7, e1002162. PMID: 21829356

3. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118

5. Mizoue, LS. et al. (1999) Biochemistry 38, 1402-14. PMID: 9931005

6. Bazan, JF. et al. (1997) Nature 385, 640-4. PMID: 9024663

7. Pan, Y. et al. (1997) Nature 387, 611-7. PMID: 9177350

8. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human CX3CL1/Fractalkine Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CX3CL1/Fractalkine Polyclonal Antibody (HX143014)

개요

이미지

참고 문헌

데이터시트

SDS