Anti-Human DCX Monoclonal Antibody (1A537) (HT416015)

Name: Anti-Human DCX Monoclonal Antibody (1A537)
Brand: abinScience
SKU: HT416015
Price: 106 USD
Availability: InStock

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개요

카탈로그 번호	HT416015
설명	Anti-Human DCX Monoclonal Antibody (1A537) [1A537] (HT416015) is a mouse monoclonal antibody detecting DCX in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
종 반응성	Human
응용 분야	ELISA, IHC, WB
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG
클론 ID	1A537
면역원	E. coli - derived recombinant human DCX (Arg178-Gly276).
타겟	Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	O43602
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	Neuronal migration protein doublecortin (DCX) is a ~40 kDa protein. Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
참고사항	For research use only.