

| 카탈로그 번호 | HY134014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human DEFA4 Polyclonal Antibody (HY134014) is a rabbit polyclonal antibody detecting DEFA4. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DEFA4 (Gly20-Asp97). | ||||||||
| 타겟 | Corticostatin HP-4, DEF4, DEFA4, Defensin alpha 4, HNP-4, HP-4, Neutrophil defensin 4 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P12838 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Defensin alpha 4 (DEFA4) is a ~10 kDa protein. Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Exhibits antimicrobial activity against Gram-negative E.coli and E.aerogenes and Gram-positive S.faecalis, S.aureus and B.cereus and the yeast C.albicans (in vitro). Interacts with pathogenic surface proteins and toxins, such as HIV-1 surface protein gp120 and B.anthracis anthrax lethal factor lef. Protects blood cells against infection with HIV-1 (in vitro). Inhibits enzymatic activity of B.anthracis lef/anthrax lethal factor (in vitro). 1. Wu, Z. et al. (2004) The journal of peptide research : official journal of the American Peptide Society 64, 118-25. PMID: 15317502 2. Ericksen, B. et al. (2005) Antimicrobial agents and chemotherapy 49, 269-75. PMID: 15616305 3. Wilde, CG. et al. (1989) The Journal of biological chemistry 264, 11200-3. PMID: 2500436 4. Gabay, JE. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 5610-4. PMID: 2501794 5. Hu, H. et al. (2019) Biochimica et biophysica acta. Biomembranes 1861, 835-844. PMID: 30658057 6. Szyk, A. et al. (2006) Protein science : a publication of the Protein Society 15, 2749-60. PMID: 17088326 | ||||||||
| 참고사항 | For research use only |
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