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| 카탈로그 번호 | HX973013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||
| 응용 분야 | IHC, IP, IF, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | K28/43 | ||||
| 타겟 | PSD-95, PSD95, Disks large homolog 4, Synapse-associated protein 90, DLG4, Postsynaptic density protein 95, SAP-90, SAP90 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P78352 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Disks large homolog 4 (DLG4/PSD95) is a ~80 kDa protein. Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. 1. Brigidi, GS. et al. (2015) Nature communications 6, 8200. PMID: 26334723 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307) |
Detects Human DLG4/PSD95 in indirect ELISAs.
SDS-PAGE for Anti-Human DLG4/PSD95 Antibody (K28/43).
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