

| 카탈로그 번호 | HC245014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human EHD3 Polyclonal Antibody (HC245014) is a rabbit polyclonal antibody detecting EHD3. Suitable for Rat, Human, and Mouse.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human EHD3 (Thr20-Ser402). | ||||||||
| 타겟 | EH domain-containing protein 3, EHD2, EHD3, PAST homolog 3, PAST3 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9NZN3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | EH domain-containing protein 3 (EHD3) is a ~60 kDa protein. ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. 1. Lu, Q. et al. (2015) Nature cell biology 17, 228-240. PMID: 25686250 2. Cai, B. et al. (2013) The Journal of biological chemistry 288, 30172-30180. PMID: 24019528 3. Naslavsky, N. et al. (2006) Molecular biology of the cell 17, 163-77. PMID: 16251358 4. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914 5. Naslavsky, N. et al. (2009) Journal of cell science 122, 389-400. PMID: 19139087 6. Waxmonsky, NC. et al. (2013) Journal of cell science 126, 3593-601. PMID: 23781025 7. Kotowski, SJ. et al. (2011) Neuron 71, 278-90. PMID: 21791287 8. Gudmundsson, H. et al. (2010) Circulation research 107, 84-95. PMID: 20489164 | ||||||||
| 참고사항 | For research use only |
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