Anti-Human EPHA2 Recombinant Antibody (SAA0832), APC (HB738137)

Name: Anti-Human EPHA2 Recombinant Antibody (SAA0832), APC
Brand: abinScience
SKU: HB738137
Price: 290 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HB738137
종 반응성	Human, Mouse
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG2a
클론 ID	SAA0832
접합	APC
타겟	Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA2, Ephrin type-A receptor 2, ECK
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
등록번호	P29317
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Ephrin type-A receptor 2 (EPHA2) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.