Anti-Human F2RL1/PAR-2 Recombinant Antibody (SAA1956) (HX041013)

Name: Anti-Human F2RL1/PAR-2 Recombinant Antibody (SAA1956)
Brand: abinScience
SKU: HX041013
Price: 196 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HX041013

종 반응성

Human

응용 분야

ELISA

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

SAA1956

타겟

GPR11, Thrombin receptor-like 1, G-protein coupled receptor 11, F2RL1, PAR-2, Coagulation factor II receptor-like 1, Proteinase-activated receptor 2, PAR2

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P55085

RRID

Anti-Human F2RL1/PAR-2 Antibody (SAA1956) (abinScience Cat# HX041013, RRID:AB_3727720)
_x005F_x005F_x000D_

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Proteinase-activated receptor 2 (F2RL1/PAR-2) is a ~44 kDa protein. Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation.

1. Cheng, RKY. et al. (2017) Nature 545, 112-115. PMID: 28445455

2. Kuckleburg, CJ. et al. (2013) Arteriosclerosis, thrombosis, and vascular biology 33, 275-84. PMID: 23202369

3. Cocks, TM. et al. (1999) Nature 398, 156-60. PMID: 10086357

4. Botham, A. et al. (2011) The Biochemical journal 438, 359-67. PMID: 21627585

5. Manithody, C. et al. (2012) Biochemistry 51, 2551-7. PMID: 22409427

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Human F2RL1/PAR-2 Antibody (SAA1956)

참고 문헌

데이터시트

Anti-Human F2RL1/PAR-2 Recombinant Antibody (SAA1956).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human F2RL1/PAR-2 Recombinant Antibody (SAA1956) (HX041013)

개요

이미지

참고 문헌

데이터시트

SDS

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