Anti-Human FBXL3 Polyclonal Antibody (HD398014)

Name: Anti-Human FBXL3 Polyclonal Antibody
Brand: abinScience
SKU: HD398014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HD398014

설명

Anti-Human FBXL3 Polyclonal Antibody (HD398014) is a rabbit polyclonal antibody detecting FBXL3. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FBXL3 (Gly37-Trp428).

타겟

F-box and leucine-rich repeat protein 3A, F-box/LRR-repeat protein 3, F-box/LRR-repeat protein 3A, FBL3A, FBXL3, FBXL3A

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9UKT7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

F-box/LRR-repeat protein 3 (FBXL3) is a ~48 kDa protein. Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.

1. Busino, L. et al. (2007) Science (New York, N.Y.) 316, 900-4. PMID: 17463251

2. Yoo, SH. et al. (2013) Cell 152, 1091-105. PMID: 23452855

3. Scott, DC. et al. (2016) Cell 166, 1198-1214.e24. PMID: 27565346

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human FBXL3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human FBXL3 Polyclonal Antibody (HD398014)

개요

이미지

참고 문헌

데이터시트

SDS