Anti-Human FBXO45 Polyclonal Antibody (HY575014)

Name: Anti-Human FBXO45 Polyclonal Antibody
Brand: abinScience
SKU: HY575014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HY575014

설명

Anti-Human FBXO45 Polyclonal Antibody (HY575014) is a rabbit polyclonal antibody detecting FBXO45 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FBXO45 (Ser41-Gly286).

타겟

F-box/SPRY domain-containing protein 1, F-box only protein 45, hFbxo45, FBXO45, FBX45

정제

Purified by antigen affinity column.

등록번호

P0C2W1

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

F-box/SPRY domain-containing protein 1 (FBXO45) is a ~30 kDa protein. Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Regulates neuron migration during brain development through interaction with N-cadherin/CDH2 after secretion via a non-classical mechanism. Plays a role in the regulation of neurotransmission at mature neurons.

1. Desbois, M. et al. (2018) The Journal of biological chemistry 293, 13897-13909. PMID: 29997255

2. Richter, KT. et al. (2020) Cell death and differentiation 27, 758-772. PMID: 31285543

3. Tsai, M. et al. (2022) The Journal of biological chemistry 298, 102698. PMID: 36379255

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-FBXO45 polyclonal antibody at FBXO45 on various samples.
Lane 1: Mouse brain lysate

참고 문헌

데이터시트

Anti-Human FBXO45 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human FBXO45 Polyclonal Antibody (HY575014)

개요

이미지

참고 문헌

데이터시트

SDS