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| 카탈로그 번호 | HW710013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1935 | ||||
| 타겟 | Diadenosine tetraphosphate synthetase, Glycine--tRNA ligase, GlyRS, Glycyl-tRNA synthetase, GARS1, Glycyl-tRNA synthetase 1, Ap4A synthetase, GARS | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P41250 | ||||
| RRID | Anti-Human GARS1/Glycyl-tRNA synthetase Antibody (SAA1935) (abinScience Cat# HW710013, RRID:AB_3727699) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Glycine--tRNA ligase (GARS1) is a ~83 kDa protein. Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis. 1. Cader, MZ. et al. (2007) FEBS letters 581, 2959-64. PMID: 17544401 2. Qin, X. et al. (2014) The Journal of biological chemistry 289, 20359-69. PMID: 24898252 3. Oprescu, SN. et al. (2017) Human mutation 38, 1412-1420. PMID: 28675565 4. Guo, RT. et al. (2009) The Journal of biological chemistry 284, 28968-76. PMID: 19710017 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human GARS1/Glycyl-tRNA synthetase Antibody (SAA1935)
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