Anti-Human GPIHBP1 Polyclonal Antibody (HP876014)

Name: Anti-Human GPIHBP1 Polyclonal Antibody
Brand: abinScience
SKU: HP876014
Price: 168 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HP876014

설명

Anti-Human GPIHBP1 Polyclonal Antibody (HP876014) is a rabbit polyclonal antibody detecting GPIHBP1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human GPIHBP1 (Ser59-Gln132).

타겟

GPIHBP1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-anchored HDL-binding protein 1, HBP1, High density lipoprotein-binding protein 1, GPI-HBP1

정제

Purified by antigen affinity column.

등록번호

Q8IV16

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is a ~19 kDa protein. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5.

1. Mysling, S. et al. (2016) eLife 5. PMID: 27929370

2. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144

3. Beigneux, AP. et al. (2009) Arteriosclerosis, thrombosis, and vascular biology 29, 956-62. PMID: 19304573

4. Coca-Prieto, I. et al. (2011) Journal of internal medicine 270, 224-8. PMID: 21314738

5. Gin, P. et al. (2007) Biochimica et biophysica acta 1771, 1464-8. PMID: 17997385

참고사항

For research use only.

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참고 문헌

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Anti-Human GPIHBP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human GPIHBP1 Polyclonal Antibody (HP876014)

개요

이미지

참고 문헌

데이터시트

SDS